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Crizotinib, a class Ia small molecule dual inhibitor of c-MET and anaplastic lymphoma kinase (ALK) had been proposed for advanced non-small cell lung cancer therapy with activation of either c-ros oncogene 1 (ROS-1) or ALK [110]

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Indeed, the integration of school subjects as a cohesive body of knowledge emphasizes the significance of their interactions, reflecting the potential to promote healthy behavior (383, 384)

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