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In brief, egg prep synchronized L1 FARD-1::RFP transgenic worms were treated with vehicle (ddH 2 O) or 4.5 mM phenformin, paralyzed with 1 mg/mL of levamisole, and then imaged in 96-well format with a Leica DM6000 microscope outfitted with a mCherry filter set and MMAF software

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Footnotes Conflict of interest: Alexander So has acted as a consultant and advisor for Novartis

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Researchers appreciate the easier handling of capsules over powder form, reducing measurement errors and contamination risks in the lab