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These include nausea (occurring in approximately 40% of patients), vomiting, diarrhoea, constipation, and abdominal discomfort

This receptor modulation triggers a cascade of intracellular signaling events that ultimately result in the activation of hormone-sensitive lipase, the enzyme responsible for breaking down stored triglycerides into free fatty acids and glycerol

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In metabolic research models, high-fat diets typically lead to hypertrophy (enlargement) of WAT cells and a slowdown in their metabolic rate

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