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91,92,93 Therefore, along with bulk compressive mechanical properties, any cartilage replacement should minimize friction and maximize shear resistance to prevent wear or implant dislodgement
HAS, hyaluronic acid synthase

Conclusions IV and IM administration of 0.05 mg/kg of buprenorphine cannot be replaced with SC administration, due to a markedly lower peak serum concentration and bioavailability with this route
Taubert D, Jung N, Goeser T, Schmig E

But that number comes with caveats that most storage guides conveniently ignore

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