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Observations such as eosinophilic muscle fibers, disruption of intercalated discs, and severe mitochondrial degradation point to a progressive degenerative process that compromises cardiac tissue integrity

The first patient delivered a healthy term girl after an uneventful pregnancy

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However, avatrombopag did increase the nadir platelet count (51 10 9 cells/L in avatrombopag group vs 29.1 10 9 cells/L in placebo group)

Additionally, TMAO can induce -synuclein misfolding, affecting neuron cells