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In light of these benefits, hybrid hydrogels assembled from both synthetic and natural components might provide a more promising avenue for therapeutic applications in CNS regrowth and engineering (Man et al., 2021

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2013 Jun;24(2):97-103

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Antioxidants inhibit extracellular matrix (ECM) synthesis of mesangial cell proteins induced by high glucose, prevent glomerular hypertrophy, reduce proteinuria, and reduce the expression of transforming growth factor-1 (TGF-1) and ECM in glomeruli of DKD animals, which is a function of oxidative stress in DKD [58,59,60]
These are also sources of vitamin A, omega-3 fatty acids, CoQ10, and other fertility supporting nutrients
