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Other key pathological changes include mesangial cell proliferation/hypertrophy, and increased production of extracellular matrix proteins [61, 64, 65]
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The subtleties, issues, and concerns about bioavailability and dose selection are dealt with in great detail elsewhere and are beyond the scope of this review [13,19,20]

It stimulates lipolysis and inhibits lipogenesis without the growth-promoting effects of full-length hGH, making it a highly targeted tool for adipose tissue and metabolic research
Biochem Soc Trans 35: 1156-1160
