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By upregulating pro-angiogenic factors such as VEGF, HIF-1 promotes the formation of new blood vessels, thereby supplying essential nutrients and oxygen for bone repair and regeneration (Zhang et al., 2022a)

tuberculosis is confined to specific cells, whether the skin diseases they cause are related to ferroptosis still requires further research ( There are strong pieces of evidence suggesting that ferroptosis exacerbates inflammation through immunogenicity, and several ferroptosis inhibitors have exhibited anti-inflammatory capabilities in various laboratory models of diseases (Kim et al., 2019)

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