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Several clinical studies reported an improvement in symptoms after ALC supplementation in patients with peripheral neuropathy of different etiologies

MnSOD, Manganese Superoxide Dismutase

10.1016/0735-1097(95)80010-E

Collectively, quercetin acts as a potent mitochondrial biogenesis enhancer and metabolic modulator through the activation of the PGC-1 axis

Alzheimers Dement (Amst) 10:41-8 2018 PMC5675717 Brinkley TE, Anderson A, Soliman EZ, Bertoni AG, Greenway F, Knowler WC, Glasser SP, Horton ES, Espeland MA, Look AHEAD Research Group

This approach has previously been used to demonstrate reductions in N-acetylaspartate (NAA), a putative neuronal marker in the hippocampus of patients with ME/CFS [74]