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The behavioral test results showed that -syn knockdown significantly alleviated the chronic hypoxia-induced decline in exploration ability to novel objects and spatial memory impairment (Fig

Devalia V, Hamilton MS, Molloy AM (2014) Guidelines for the diagnosis and treatment of cobalamin and folate disorders

Given that inflammatory insults do not cause depressive symptomology when KP enzymes are blocked, one can surmise that the generation of KP metabolites is a mandatory event preceding the induction of MDD manifestation [117]