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Cabello S

Brimonidine has a unique mechanism of action that primarily acts on receptors in the veins, whereas other redness relievers (formulated with ingredients like tetrahydrozoline) also target receptors in the arteries

These operate through completely different pathways

For instance, VEGF inhibitors have been applied in clinical practice, and their efficacy has been validated in various cell lines (such as A549 and U251) and animal models (including H22)

Studies have revealed the presence of IL17secreting cells across all AA types, with a higher prevalence observed in multiple patchy alopecia and a lower occurrence in AT, predominantly localized in the periphery of the hair follicle [74]

For a summary of the worker findings, see Table 1