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Recently, in the bile duct ligation-induced liver cirrhosis (Sever et al., 2019), no portal hypertension development and reversal of the already preexisting portal hypertension to normal values (Sever et al., 2019) have become possible

Importantly, serum glucagon levels were significantly lower in AAV-sh-VGF-injected mice compared to controls (Fig

doi: 10.3109/0886022X.2012.723661

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The perturbation of cellular glutathione homeostasis was achieved by exposing hepatocytes to H 2 O 2 , which is a well-established method of inducing intracellular glutathione imbalance