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Vitamin B12 Deficiency & Chronic Disease Vitamin B12 deficiencies are associated with chronic diseases

This is likely due to selective inhibition of envelope glycoproteins, specifically the major such protein, gp120, rich in intra chain disulfide bonds

A similar degradation process is also involved in the metabolism of glutathione S-conjugate with an aromatic compound, which is finally metabolized to mercapturic acid via the N-acetylation of the cysteine S-conjugate, and is then excreted from the body through the urine