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A study in mice revealed that betaine can restore the function of adipose tissue and sensitivity to insulin, and these effects may be attributed to the alleviation of endoplasmic reticulum stress (Reference Wang, Yao and Pini34)

Calabrese, V., Cornelius, C., Mancuso, C., Lentile, R., Stella, A

Intravenous ketogenic diet therapy for neonatal-onset pyruvate dehydrogenase complex deficiency
