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These findings were seen in both a retrospective cohort and a validation cohort

Shlipak MG, Simon JA, Vittinghoff E, Lin F, Barrett-Connor E, Knopp RH, et al

Mitochondria are abundant both in the brain and muscles

N Engl J Med 383(4):334346 Abrams JY, Godfred-Cato SE, Oster ME, Chow EJ, Koumans EH, Bryant B et al (2020) Multisystem inflammatory syndrome in children associated with severe acute respiratory syndrome coronavirus 2: a systematic review

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( i ) Quantification of H2AX foci in cells expressing empty vector or CCNE1 transduced with shRNAs targeting TMLHE alone (shTMLHE) or supplemented with propionylcarnitine or butyrylcarnitine (n = 3 technical replicates representative from 2 independent experiments in each cell line)