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Prognostic Significance of Multidrug Resistance-Related Proteins in Childhood Acute Lymphoblastic Leukaemia

Both male hemizygotes and female homozygotes with G6PD gene deficiency manifest show significantly reduced G6PD enzyme activity, while 80% of female heterozygotes show moderately reduced G6PD enzyme activity
Under oxidative stress, GSH is converted by GSH-dependent peroxidases into GSSG upon its reaction with ROS

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doi: 10.1007/s00726-008-0210-y
