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The fact that L-carnitine supplementation didn`t add to the patients` seizure control was previously reported by Selter and collaborators who studied carnitine supplementation as one of dietary modifications to improve seizure control in patients on KDT and reported that this dietary modification wasn`t ideal for improving seizure control 24

The Comedown The "comedown" is the feeling of the effects of a drug gradually wearing off, after a period of intoxication

10.1371/journal.ppat.1004109 74 GuiralS.MitchellT

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When you are started on methotrexate, ask about your doctor's practice for monitoring and follow-up