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B vitamins, including B1 (thiamine), B2 (riboflavin), B3 (niacin), B5 (pantothenic acid), B6 (pyridoxine), B7 (biotin), B9 (folate), and B12 (cobalamin), are essential nutrients that play a critical role in energy production and metabolism

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Supporting the existence of an additional cyclin D-Rb docking interaction, truncation of the Rb C terminus disrupts phosphorylation by cyclin D1-Cdk4 in vitro, and this truncated Rb variant slows division and inhibits E2F-dependent gene expression in cultured cells (Gorges et al., 2008

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