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The GCL enzyme is a heterodimer formed by two subunits: the heavy subunit or glutamate cysteine ligase catalytic subunit (GCLC, 73 kDa) and the light subunit or glutamate cysteine ligase modulating subunit (GCLM, 30 kDa)
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55 The newly synthesized BMP-7, but not BMP-4, activates p-Smad1/5, subsequently inducing the expression of the chondrocyte-specific transcription factor Sox9
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How often are injections needed after repletion
