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The specific cleavage of DEVD by caspase-3 generated the hydrophobic TPS residue, which aggregated, resulting in restriction of intramolecular rotations of the phenyl rings and ultimately leading to fluorescence enhancement (Figure 2A) 77

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Ubiquitin C-terminal hydrolase-L1 (UCH-L1) as a therapeutic and diagnostic target in neurodegeneration, neurotrauma and neuro- injuries

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