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NAD+/NADH redox alterations reconfigure metabolism and rejuvenate senescent human mesenchymal stem cells in vitro

Knockdown of HIF-1 significantly increases intracellular ROS and apoptosis levels (Xu, 2018), likely through the upregulation of anti-apoptotic factors or modulation of metabolic pathways

Since DHEA is a building block for this hormone, maintaining healthy adrenal gland/HPA axis function also helps

[DOI] [PubMed] [Google Scholar] 250.Ota S., Morita A., Ohnuki S., Hirata A., Sekida S., Okuda K., Ohya Y., Kawano S

doi: 10.3390/molecules28093814

W., Zhao, J
