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However, a recent study found that an alternate mechanism may also be involved in the development of NTDs independently of one-carbon metabolism

Mice fed a low-magnesium diet had also a lower mRNA content of factors controlling the gut barrier function in the ileum (zonula occludens-1, occludin, proglucagon) and a 2-fold higher mRNA content in the liver and/or intestine of TNF-, IL-6, CCAAT/enhancer binding protein homologous protein, and activating transcription factor 4, reflecting inflammatory and cellular stress

However, the handful of studies available is promising

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TLK-199 Telik

L., Holtzclaw W
