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Similarly, the quinolinium containing parent analogue 1-MQ also lacked passive diffusion properties (Table 1), suggesting that the lipophilicity and drug-like permeability properties of analogues within the methylquinolinium series had to be improved via chemical modification

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The consistently reported poor diagnosis and treatment experience encountered in UK Primary Care by people with a diagnosis, or symptomatic of, Pernicious Anaemia in the UK is well documented and reported on in research carried out and published by the Pernicious Anaemia Society