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Increase of fat oxidation and weight loss in obese mice caused by a synthetic GH fragment, AOD9604

In both patients, normal vitamin B12 levels were achieved, and symptoms of its deficiency disappeared

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Cardiovascular safety has been specifically evaluated through thorough QT studies, which demonstrated no clinically relevant QTc prolongation, indicating no increased risk of ventricular arrhythmias

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Severe ECG disturbances (i.e., severe bradycardia and ST-elevation until asystole) were also reversed