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Science 13 , 163172 (2019)
An increased proportion of PUFAs in normal diet also induces oxidative stress (increased malondialdehyde [MDA]), reduces cellular defense against oxidative stress (metallothionein) in the liver, and promotes oxidative degradation of DNA (elevated 8-hydroxy-2-deoxyguanosine levels serum) in a content-dependent manner despite increased fat oxidation and decreased fat synthesis [80]
These levels quickly dropped to below 80 ng/g brain tissue by 1 h and were undetectable after 4 h
Most biologists have been led astray by evolutionary theory
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Both types of therapies include corticosteroids, intravenous immunoglobulins (IVIg), immunosuppressants, plasmapheresis, and rituximab, either alone or in combination [19, 22]
