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The remarkable anti-tumor efficacy of CUR/miR155@DssD-Hb NPs may be attributed to the direct cell-killing effect of CUR and the reprogramming of the immunosuppressive TME facilitated by miR155 and CUR

Li Y, Wu KJ, Yu SJ, Tamargo IA, Wang Y, Greig NH

A study using a three-dimensional tumour sphere model combined with CRISPR-Cas9 screening reported that Nrf2 overactivation was essential for lung tumour proliferation and survival, whereas silencing of Nrf2 predisposed spherical cells to ferroptosis, which was also consistent with clinical observations [77]

It is a method that also examines the quaternary structure of purified proteins

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Then, Fe 2+ is released from the endosome to cytoplasm with the assistance of SLC11A2 (also known as DMT1)
