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Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimers disease in rodent models

They damage any proteins they come into contact with and the accumulation or build-up of these radicals and the damage they create causes oxidation (modifications to your proteins, lipids and DNA.) [1] An example of how free radicals could harm skin cells is a condition called idiopathic guttatehypomelanosis

[DOI] [PubMed] [Google Scholar] 95.Akimov M.G., Fomina-Ageeva E.V., Dudina P.V., Andreeva L.A., Myasoyedov N.F., Bezuglov V.V

It actually helps detoxify the liver and protect it from damage
Haining RL, Hunter AP, Veronese ME, Trager WF, Rettie AE