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Parkinsons disease is associated with hippocampal atrophy

Indeed, Grx1 knockout mice show increased glutathionylation and loss of function of DJ-1 which, in SH-SY5Y and C

Acyl-CoA synthetase long-chain family member 4, a key enzyme in phospholipid metabolism, facilitates the conversion of PUFAs, such as arachidonoyl and adrenic acid, into PUFA-CoA (25)

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Currently, chlorogenic acid is considered a promising hepatic detoxifier for APAP