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When it comes to antioxidants, more is not always better
A mechanistically curious reader is left to reconstruct the gastric story from receptor biology, pramlintide analogy, animal work, and side-effect patterns, rather than from a direct, cagrilintide-specific, longitudinal emptying dataset

A Western diet further exacerbates this effect by increasing the level of ROS, which induces Enpp2 (ATX) expression in enterocytes and aortic endothelial cells, increasing systemic and local LPA levels

The role of the EAAT3 is to control glutamate spillover, which affects pre-synaptic N -methyl- D -aspartate (NMDA) and metabotropic glutamate receptors activity 63,64

Mitsis T, Efthimiadou A, Bacopoulou F, Vlachakis D, Chrousos GP, Eliopoulos E
