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Sequence: Gly-His-Lys (3 amino acids) complexed with Cu(II) Molecular formula: C14H24N6O4Cu Molecular weight: 403.92 g/mol Copper content: 14-16% by weight Blue lyophilized powder (color indicates proper Cu(II) coordination) HPLC and mass spectrometry verified 100 mg larger format for extended research protocols For laboratory research only

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Nevertheless, the discovery of an extra-hepatic IGF-I production in the following years[18, 45], made it necessary to spand the conception of the GH/IGF-I axis, being well accepted nowadays that pituitary GH is able to induce IGF-I synthesis in both liver (~75%) and other tissues[23, 46, 47], which subsequently, is able to act in an endocrine/paracrine/autocrine manner

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At the genus level, hypertensive individuals exhibit a substantial decrease in the relative abundance of Faecalibacterium, alongside an increase in the relative abundance of Enterococcus and Streptococcus, implying a potential association between hypertension and gut dysbiosis [39]

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