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p = 0.023), specifically lower thalamus, putamen, caudate, and accumbens volume and with poorer scores on tests of non-verbal memory, motor skills and response time ( = -0.432+6.470;p = 0.012, = -0.364+3.855;p = 0.037, = -0.467+3.139;p = 0.006, respectively)

It is thought to interact with growth factors and cytokines, which are important signaling molecules that regulate cell growth, differentiation, and inflammation

10.1007/s12035-016-9924-0 66

However, this protective mechanism can be commandeered under pathophysiological conditions

Apr 2019;7(2):272-276

Clinically, aging often shows up first as changes in the bodys underlying regulation, including sleep quality, recovery capacity, inflammation patterns, and the stability of cellular repair processes