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doi: 10.1016/j.biopsych.2020.03.016 22 StrassnigMSingh BrarJGanguliR
Studies consistently show minimal side effects, mostly limited to mild nasal irritation when using the spray form

The recovery benefits are most apparent in people who actually stress their bodies

Inside cells, TUDCA seems to act in other ways by: Reducing endoplasmic reticulum (ER) stress Calming inflammatory signals TUDCA helps keep NF-B a master switch for inflammation from becoming overactive during cellular stress
The difference between us was not willpower or fitness or even sensitivity, it was likely a bag of magnesium and B vitamins and the decision to treat depletion as a problem to solve rather than a personal failing

This action results in a reduction of melanin content in the epidermis and could potentially help lighten the periorbital area, although clinical studies would be necessary to confirm this
