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Shows that PARylation facilitates GG-NER through stabilization of DDB2 and recruitment of the chromatin remodeller ALC1

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Abstract Cis-diamminedichloroplatinum (II) (cisplatin) is a widely used anti-tumor drug for the treatment of a broad range of human malignancies with successful therapeutic outcomes for head and neck, ovarian, and testicular cancers

One-third of NFL teams are using acupuncture to aid injury recovery and treat pain

Mice were acclimatized in a clean-grade animal room under 12 h/ 12 h light and dark cycle at a constant temperature (23 2 ) and humidity of 50 10% and were provided with standard chow and water ad libitum