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Bibcode:1993PNAS...9010957G

Evolutionary pressure made pathogens exploit the mitochondrial influence in killing and developed mechanisms to disturb mitochondrialnucleus communication in fighting infections and increased the survival of the struggling pathogens ( The existence and optimal functioning of pattern-recognizing receptors (PRRs) are essential for optimal immune functionality

12Lu SC

PMID: 15606130

J Biol Chem 277(23):2033620342
