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Description
Conclusion: L-carnitine supplementation does not significantly change and improve the serum lipid profile, including TG, TC, HDL, LDL, and VLDL levels
In IR there is impaired signaling via the phosphoinositol-3 kinase pathway allowing the buildup of toxic lipid metabolites, such as FA acyl CoA, diacylglycerol, and ceramide in numerous tissues including the liver, pancreatic beta cells, and adipocytes [81]
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