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doi: 10.1016/j.jconrel.2006.08.013

These tools reduce the cognitive load of managing complex dosing protocols and provide built-in safety checks that flag unusual measurements before they become errors

Regulators have shown they are willing to proceed incrementally, product by product, while reserving the ability to escalate to systemic action where warranted

Di Pietro et al, 2020)

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While UK healthcare professionals can, in exceptional circumstances, prescribe unlicensed medicines under the MHRA 'specials' framework, this would rarely be appropriate for ED given the availability of licensed, evidence-based alternatives