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ImmTOR induces a tolerogenic phenotype in dendritic cells in the spleen 9 and in liver sinusoidal endothelial cells and other APCs in the liver 12 (Fig

While they can provide significant relief from pain and inflammation, they are not a standalone solution

PMCID: PMC9531956

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3.2.4 Pro-inflammatory factors Appropriate activation of the inflammatory response is essential for defense against injuries, but if not properly regulated, deleterious effects may occur (81)

Fukuda K, Straus SE, Hickie I, Sharpe MC, Dobbins JG, Komaroff A (1994) The chronic fatigue syndrome: a comprehensive approach to its definition and study