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Indeed, a review of the preclinical evidence for MET inhibitors in pancreatic cancer acknowledged that none of the preclinical cancer models had considered the role of the stroma in MET/HGF pathway signalling [91]
2007;292(3):E8919
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These stress fibers can also act as a platform for the assembly of other stress fibers within the cell [62]
9 BenkhouchaM.MolnarfiN.Dunand-SauthierI.MerklerD.SchneiterG.BruscoliS.et al (2014)
Unfortunately, prolonged damage to myelin is often irreversible
