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Description
It is induced by activation of NMDARs (and sometimes voltage-gated calcium channels) and modulated by GABA B receptors, which together drive an increase in cytoplasmic calcium, in part by triggering the release of calcium from intracellular stores

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However, in a world of plenty, this advantage would turn into a disadvantage and give fast increases in body weight, hyperinsulinemia, and the development of metabolic syndrome problems early on (reviewed by Dunger et al (48)

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