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HCG protocols, by contrast, carry risks that intensify with duration: electrolyte imbalance, thyroid suppression, and severe rebound weight gain upon discontinuation

It acts on the LH/hCG receptor (LHCGR) and is widely used in endocrinology research as a stimulus for steroidogenesis and a model ligand for glycoprotein-hormone receptor signaling

This study aimed to elucidate how LD manipulation affects macrophage phenotypes and functions, with a focus on their role in efferocytosis and inflammatory modulation