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The mechanism differs as well: Dihexa acts as a hepatocyte growth factor (HGF) mimetic promoting synaptogenesis, while Semax modulates BDNF expression and P21 acts through CNTF pathways

doi: 10.1016/s0939-6411(00)00090-4

Xue, Y., Wen, M., Xu, J., & Yanagita, T

Cumulative evidence points at alterations in neurotransmitter systems in fibromyalgia, which influence pain perception, fatigue, sleep disturbances, and depressive as well as anxiety-related symptoms (Figure 1)

The activation of AMPK during glucose deprivation initiates a protective mechanism against ferroptosis, mainly inhibiting PUFA biosynthesis [44, 45]

this suggests that the DAT function is critical in preventing diet-induced obesity 47