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doi: 10.3324/haematol.2019.217083 199 SwystunLLMukherjeeSLiawPC

Nicotinamide Adenine Dinucleotide (NAD+) is a coenzyme found in every cell of your body, playing a vital role in energy production, cellular repair, and healthy aging

In this syndrome, the lack of lipoic acid, due to the defective activity of lipoic synthase, causes the subsequent impairment in lipoid acid-dependent enzymes, such as PDH and KDH [126]