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The complex pharmacological profile of Ashwagandha, especially its principal bioactive constituent Withaferin A, stems from its context-dependent regulation of key cellular signaling nodes, with the mitochondria acting as the central control organelle

Additionally, dosage, formulation, and duration variations of herbal interventions make it difficult to standardize therapeutic recommendations

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After traumatic brain injury, MCT2 expression is induced in cerebral vasculature, correlating with increased cerebral KB uptake [47]

Total protein concentration was measured using the DC Protein Assay (Bio-Rad Laboratories, Inc., Hercules, CA, USA) according to the manufacturers instructions