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Neurotoxicity was almost completely prevented by the presence of either NMDA receptor antagonists, MK-801 and D(-)-2-amino-5-phosphonopentanoic acid (D-AP5), or mGluR antagonist, (S)-4-carboxyphenylglycine (S-4CPG)

Metformin, an example of a repurposed drug with growing interest for its potential to target tumor metabolism, is a first-line treatment for type II diabetes (Wrth et al., 2013

Red blood cells have been particularly susceptible to oxidative stress due to their constant exposure to oxygen and elevated iron levels

The need for Vitamin B12 is increased by pregnancy and lactation

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Individual patient characteristics also play crucial roles