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In the same group, B12-downregulated genes had GO annotations related to NF-kappaB signaling, T-cell receptor signaling pathway and negative regulation of histone H3-K9 trimethylation ( Figure S3 )

if it is extremely low, good methylation can be assumed

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A representative full cycle: On (812 weeks): 4 weeks daily 4 weeks at 5/week remaining weeks at 23/week maintenance

This involves the conversion of homocysteine to methionine, preventing its accumulation in the body