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A phase 1, randomized, double-blind, placebo-controlled, crossover study to evaluate the pharmacodynamic effects of VX-150, a highly selective Na V 1.8 inhibitor, in healthy male adults

For the remainder of this section, we will focus on parvalbumin chandelier cells since these are the interneurons known to play a major role in prefrontal cortexdependent working memory and also have been implicated in the pathophysiology of neuropsychiatric disorders such as schizophrenia [60, 62]

PLoS ONE 8 , e70822 (2013)

This supplement stands out for several reasons

Stupnisek et al., 2012, 2015

Alkylation is the chemical process of introducing one or more alkyl groups into a protein or compound