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The damage to the macrovascular system which manifested as cardiovascular disease, is the primary cause of the mortality associated with diabetes 8

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However, several limitations should be acknowledged: (i) the limited sample size reduces the generalizability of the findings and prevents establishing causal links regarding sex or mutation-specific metabolic alterations

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Lymphocyte loss and immunosuppression following acetaminophen-induced hepatotoxicity in mice as a potential mechanism of tolerance

5 g RS given twice a day orally) compared to solely dietary instructions (high-fibre diet) was evaluated in a group of 57 PD patients (of whom 32 received RS and 25 dietary instructions only) and 30 control subjects receiving RS (the RESISTA-PD trial, ClinicalTrials.gov ID: NCT02784145) [103]