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Inflammation and Oxidative Stress in Diabetic Kidney Disease: The Targets for SGLT2 Inhibitors and GLP-1 Receptor Agonists

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Edaravone is used in the treatment of stroke and amyotrophic lateral sclerosis in some countries

Chronic uremia inhibits the proliferation of endothelial progenitor cells, which are crucial for vascular repair

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Apos-mediated the activation of ECs may generate multiple cytokines, such as interleukin (IL)-6, IL-8, intercellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1) and so on, which incite the recruitment of monocytes and adhesion to ECs 17-19