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G., et al., Mediterranean Diet Adherence, Gut Microbiota, and Alzheimer's or Parkinson's Disease Risk: A Systematic Review, Journal of the Neurological Sciences 434 (2022): 120166

Previous studies [9, 10] have demonstrated that oral folinic acid, oral trimethylglycine, and subcutaneous injections of methyl Vitamin B12 were able to greatly improve methylation, glutathione, and oxidative stress, similar to the results here

Lack of these two proteins can prevent lysosomal biogenesis and autophagosome maturity, leading to the ganglioside accumulation and neuronal death 124

The spectrum of mutations in the PCFT gene, coding for an intestinal folate transporter, that are the basis for hereditary folate malabsorption