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Description
The latter experimental setup resembles the situation of humans affected by NF2 disease, where one copy of the Nf2 gene is lost in the entire body due to a germline mutation [30]

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15 We found that the seip-1(-) mutants did not form enlarged LDs when fed with JUb74, suggesting that the recruitment of SEIP-1 by PUFA was required for LD expansion under the BCFA-rich diet (Figure 6I)